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Exercise reduces the amount of calories burned at rest in people with obesity, according to a new study by researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences and the University of Roehampton.

The study, published in Current Biology on August 27, found that people who exercise burn fewer calories on body maintenance, where to buy generic tenormin canada no prescription therefore markedly reducing the calorie burning gains of exercise. This reduction in energy burned at rest was most pronounced in individuals with obesity and also, to a lesser extent, in older adults.

Analysis based on data from 1,750 adults in the IAEA doubly labeled water database showed that in individuals with the highest BMI, 51 percent of the calories burned during activity translated into calories burned at the end of the day. For those with normal BMI, however, 72 percent of calories burned during activity were reflected in total expenditure.

The researchers investigated the effects of activity on energy expenditure and how these effects differ between individuals.

“When enrolled into exercise programs for weight loss, most people lose a little weight. Some individuals lose lots, but a few unlucky individuals actually gain weight,” said Prof. John Speakman from SIAT, co-corresponding author of the study.

The reason for these individual responses is probably because of what are called compensatory mechanisms. These include eating more food because exercise stimulates our appetite, or reducing our expenditure on other components like our resting metabolism, so that the exercise is in effect less costly.

“But we wanted to find out why some people show such compensatory mechanisms and others don’t,” said Prof. Lewis Halsey from the University of Roehampton in the UK, lead author of the study. The analysis found that two things dominate the extent of compensation. One is age–older people compensate more. The other is obesity specifically; people living with obesity cut back their resting metabolism when they are more active. The result is that for every calorie they spend on exercise they save about half a calorie on resting.

This is a cruel twist for individuals with obesity. For such people, losing weight by increasing activity is likely to be substantially harder than for a lean person, whose compensation is much less and whose need to lose weight is much lower.

“Around the world, national guidelines tend to recommend a 500–600 calorie deficit through exercising and dieting to lose weight. However, they do not take into account the reduction of calories being burned in the most basic of human functions as the body compensates for the calories burned on the exercise,” said Prof. Halsey.

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