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Nonpharmacologic interventions effective for pediatric migraine

Components of nonpharmacologic interventions may be effective for treating pediatric migraine, according to a review recently published in Pediatrics.

Helen Koechlin, Ph.D., buspar klonopin together from the University of Basel in Switzerland, and colleagues conducted a systematic review and network meta-analysis to examine whether nonpharmacologic treatments are more effective than waiting list for children with migraine. Data were included from 12 studies with 576 participants.

The researchers found that self-administered treatments, biofeedback relaxation, psychological treatment, and psychological placebos were significantly more effective than waiting list when interventions were classified into groups based on the similarity of treatment components; the effect sizes varied from standardized mean differences of 1.14 (95 percent confidence interval, 0.09 to 2.19) to 1.44 (95 percent confidence interval, 0.26 to 2.62) for long-term psychological placebos and short-term self-administered treatments, respectively. However, none of the interventions were significantly more effective than waitlist control when all interventions were examined individually, mainly due to lack of statistical power.

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